What to Expect from Your First Spravato® Session

Ashley Keays • October 2, 2025

What to Expect from Your First Spravato Session

Starting a new treatment can feel overwhelming - especially when it comes to your mental health. At Creative Wellness TMS, we want you to feel confident and prepared before beginning Spravato® (esketamine) nasal spray treatment. Here’s what you can expect during your first session.

Before Your Appointment

  • Consultation & Evaluation: You’ll meet with a provider to confirm that Spravato is right for you, review your medical history, and go over what the treatment involves.


  • Insurance & Cost: Many patients are eligible for insurance coverage. For those without coverage, the cost is $250 per visit.

During the Session

  • Administration: You’ll self-administer Spravato nasal spray under the direct supervision of our trained medical team.


  • Observation Period: After dosing, you’ll remain in a comfortable treatment space for about 2 hours while our team monitors your safety and well-being.



  • Possible Sensations: Some patients experience mild dizziness, disorientation, or drowsiness. These effects usually resolve within the observation period.

After the Session

  • Transportation: You will need someone to drive you home - you should not operate a vehicle the same day as treatment.


  • Follow-Up Care: Your provider will check in on your progress and adjust your treatment plan as needed. Most patients attend twice-weekly sessions at the start, gradually reducing frequency as improvement continues.

Why Spravato at Creative Wellness TMS?

  • Safe, supportive environment
  • Experienced providers trained in interventional mental health
  • Personalized care plans that go beyond symptom relief

Ready to Take the Next Step?

If depression has not improved with other treatments, Spravato may offer the breakthrough you’ve been waiting for. Schedule your consultation today and find out if Spravato is the right option for you.

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