Depression, the Chameleon, Often Needs Unconventional Treatment

Ashley Keays • May 16, 2025

...Can you imagine feeling better after a lifetime of depression?

Depression is a complex diagnosis that doesn't manifest uniformly; it's almost like a chameleon. While many associate it with sadness, tears, and despair, it can present differently—restless sleep, difficulty concentrating, lack of motivation, or losing interest in once-enjoyed activities. Recognizing the varied faces of depression is the first step in aiding and advocating for those who might struggle silently. Some individuals are aware of their depression but hesitant to share, while others may feel life is not worth living.


In addressing depression, especially treatment-resistant cases, the challenge lies in finding effective solutions. Standard medication often falls short, with a significant percentage not achieving the desired outcome. Traditional therapy remains a viable option, but exploring alternatives that may even seem unconventional is crucial. This is where Creative Wellness TMS comes in… we look at every patient through a different lens; we know by the time you come to see us you’ve tried multiple medications, you’ve tried talk therapy, and we know you’re emotionally exhausted. There are other things out there….


Genetic testing has transformed the landscape of medication management. Individualized medication selection uses your unique genetic profile to guide treatment decisions—offering valuable insights for more effective, personalized care, especially in cases of treatment-resistant depression. While this approach holds promise, individual medication responses can still vary widely. However, it brings us closer to a more effective and appropriate treatment plan earlier in our mental wellness journey than ever before.


Beyond medication, alternatives like transcranial magnetic stimulation (TMS) provide a non-invasive method to stimulate the natural function of the brain’s neurotransmitters especially in the specific areas of the brain that control mood. When we experience depression, the synapses in those mood-regulating areas are underactive and connections are broken.  TMS revitalizes those dormant synapses, “waking up” the brain to function as it was meant to function. This treatment changes lives.  TMS is an FDA-approved therapy, that can be used in conjunction with medication without medication.  There is an impressive two-thirds remission rate after a single course of 36-treatments. Imagine feeling better after a lifetime of depression…


Spravato, nasal eketamine, has also entered into the mental health arena. It is a unique antidepressant that targets the NMDA receptors. In addition to balancing the neurotransmitter glutamate, the key component, esketamine, is recognized for rebuilding synapses – or connections – between brain cells similar to TMS.  This provides a much faster result, often within days rather than weeks.  Can you imagine starting to feel better sooner?


There are many alternatives to traditional medications.  We would love to introduce these options to you. Schedule an appointment with us today for the next step in your journey toward a healthier, HAPPIER you.

Not Sure Where to Start? We Can Help

With so many treatment options, finding the right one can be overwhelming. Let’s make it easier. Answer a few quick questions, and we’ll help you discover what might work best for you

Take the Quiz →
By Ashley Keays December 12, 2025
Is TMS Therapy Safe?
By Ashley Keays December 12, 2025
What Is TMS Therapy?
By Ashley Keays November 14, 2025
A supportive guide for mothers navigating emotional changes after childbirth
By Ashley Keays November 14, 2025
A Guide for Parents Who Want to Help Their Child Feel Safe, Supported, and Understood
By Ashley Keays November 13, 2025
Anxiety, trauma, and anger are deeply human experiences - but when they begin to interfere with daily life, relationships, or your sense of control, it may be time to seek support. At Creative Wellness TMS , we work with individuals facing emotional overwhelm, mood instability, and trauma-related symptoms, helping them regain stability and find relief through evidence-based treatments and compassionate care. Whether you’re navigating long-standing challenges or a recent shift in your mental health, understanding the signs and knowing when to reach out is the first step toward healing.
By Ashley Keays November 13, 2025
If you’ve been researching TMS therapy for depression , anxiety, or OCD, one of the first questions that probably comes to mind is: “Will my insurance cover it?” At Creative Wellness TMS , we understand that cost can be one of the biggest barriers to seeking care. That’s why we believe in being open and transparent about coverage, pricing, and what to expect - so you can focus on your health, not paperwork.
By Ashley Keays November 12, 2025
Restoring Hope for Those Who’ve Served
By Ashley Keays October 30, 2025
If you’ve been exploring options for treating depression or anxiety, you may have come across both talk therapy and TMS therapy. While they’re powerful on their own, research shows that the combination of the two can lead to the most sustainable, long-term improvement in mental health. At Creative Wellness TMS, we believe in a blended approach - where brain-based treatments and emotional support work hand-in-hand.
By Ashley Keays October 10, 2025
Understanding OCD and Its Challenges
By Ashley Keays October 2, 2025
What to Expect from Your First Spravato Session